Towards a large-scale high-confidence binary protein interaction network for Drosophila. Genome is arguably the best-annotated multi-cellular eukaryotic genome and yet, there remains much to be learned about the functions of Drosophila. Moreover, an ultimate goal of biology is not just to understand individual protein activities but also to develop quantitative models that can describe biological systems on a global scale i.

Protein-protein interaction networks are spatially and temporally merged from the results of various experimental and predicting methods. These often ignore localization data, which in turn deteriorates the data quality and its predictive potential. We present ComPPI, the compartmentalized protein-protein interaction database. Which provides qualitative information on the interactions, proteins and their localizations.